Author

M. García-Domínguez

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Review Open access Aug 2026

Activating Transcription Factor 3 in Pain: A Molecular Regulator and Emerging Biomarker

Pain is a complex process involving dynamic transcriptional changes in cells of the PNS and CNS following injury or inflammation. Among stress-inducible transcription factors, ATF3 has emerged as one of the most robust molecular markers of neuronal injury, particularly in sensory neurons of the DRG. Although ATF3 is wi...

M. García-Domínguez · Genes · 0 citations

Open access Sep 2026

TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment

This study provides evidence for a key role of TNFR1, as expressed by malignant cells, in orchestrating a pro-tumor immunosuppressive environment through secondary inflammatory mediators. Results highlight the relevance of interfering TNFα/TNFR1 in cancer immunotherapy.

Elixabet Bolaños, Lorena Cañas-Zabala, Irene Olivera et al. · Journal of Experimental Medi... · 0 citations