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M. Hassan

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#protein folding Review Oct 2026

Targeting protein misfolding and aggregation in neurodegenerative diseases: challenges for the identification and validation of targets for small molecules.

The mechanisms of protein folding, misfolding, aggregation, and prion-like propagation in major neurodegenerative proteinopathies, including amyloid-beta and tau in Alzheimer's disease, alpha-synuclein in synucleinopathies, TDP-43 and FUS in ALS/FTLD, polyglutamine-expanded proteins, prion proteins, and rare hereditary...

A. Choudhury, Sneh Prabha, Mohammad Umar Saeed et al. · 0 citations
Review Sep 2026

Targeting the Candida albicans agglutinin-like sequence 3 adhesin to disrupt oral polymicrobial bacterial-fungal biofilms: mechanisms and therapeutic strategies.

This review examines the molecular architecture and domain organization of Als3, including the N-terminal peptide-binding cavity (PBC) and the amyloid-forming region, as well as the regulatory network controlling ALS3 expression, which is one of the few targets for which a single treatment can act on both the fungal an...

A. Javaid, Nazia Tabassum, Y. M. Siddiqui et al. · 0 citations
Open access Aug 2026

Elucidating the Antiglycation Potential of Plumbagin Against Methylglyoxal-Induced Glycation of Bovine Liver Catalase.

These findings highlight plumbagin as a potent multifunctional compound capable of mitigating MGO-induced glycation, and highlight plumbagin as a potent multifunctional compound capable of mitigating MGO-induced glycation.

Faiza Iram, Ayesha Aiman, Deepanshi Vijh et al. · 0 citations

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