Background/Objectives: AP-2 transcription factors are increasingly recognized as key regulators in cancer biology. The TFAP2E gene, which encodes the AP-2ε transcription factor, remains understudied in cancer compared with other AP-2 family members. The scarcity of studies examining potential AP-2ε targets and related...
D. Kołat, Julia Gałęziewska, Paulina Buczek et al.· Cancers· 0 citations
The results indicate that MM compounds exhibit measurable anticancer activity in 3D spheroid models and that their combination with ATM inhibition modulates both viability and spheroid morphology, as reflected by changes in ATP levels, core size, and diffusion parameters.
M. Kciuk, Katarzyna Wanke, M. Mojzych et al.· Scientific Reports· 0 citations
This review examines the emerging data on envafolimab and discusses strategies to optimize its therapeutic impact, including combination regimens and personalized approaches.
M. Kciuk, D. Kołat, Katarzyna Wanke et al.· Frontiers in Immunology· 0 citations
This review examines how stemness-associated signaling pathways, including Hedgehog, Notch, and Wnt/ β -catenin, interact with DDR programs to promote CSC survival under genotoxic stress, and summarizes current and emerging therapeutic strategies targeting CSC-specific DDR dependencies.
M. Kciuk, Julia Gałęziewska, Weronika Kruczkowska et al.· Oncology Research· 0 citations
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