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Author

M. R. Shah

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#protein folding Open access Nov 2026

A pragmatic approach to combat lipotoxicity in HepG2 cells: Engineering of curcumin loaded polydopamine coated Zn-MOF

Polydopamine-coated Zn-MOF-based curcumin delivery is a promising approach for further investigation of NAFLD/NASH, and curcumin activity in an in vitro HepG2 lipotoxicity model is improved by reducing oxidative stress and lipid accumulation while supporting PREP inhibition and favorable gene expression changes.

Abdul Jabbar, Khair Ullah, A. Balouch et al. · 0 citations
Oct 2026

Nano-Emulsification and Soft Gel Encapsulation to Improve the Delivery of Anti-Diabetic Drug Ertugliflozin-L-Pyroglutamic Acid via SNEDDS: An In Vitro Assessment using RP-HPLC.

OBJECTIVE This study aim to develop and evaluate a novel soft gelatin capsule formulation of Ertugliflozin-L-Pyroglutamic Acid (ERT) using a self-nanoemulsifying drug delivery system (SNEDDS) to enhance its solubility, physicochemical stability, and in vitro drug dissolution relative to the commercial Steglatro® tablet...

Muhammad Ashraf, Mohsin Ali, R. Zairov et al. · 0 citations

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