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Author

M. Rettel

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Open access Aug 2026

Granule microenvironment regulates the dual functions of FMR1

It is shown that the condensation propensity of FMR1 containing granules regulates the two antagonistic functions, such that phase separation by FMR1-CTD creates the molecular microenvironment necessary for the repressive activity, whereas reduction in phase separation is associated with increased translation.

Vaishali Grewal, Frank Wippich, Danilo Lüdke et al. · 0 citations
Open access Jul 2026

Intrinsic flexibility of Type VII secretion central pore is required for substrate translocation

The functional roles of several central pore-forming residues in mediating secretion are probed and their crucial role in ESX-5 substrate translocation efficiency is demonstrated and shown to be general valid for these systems.

Christin Ritter, Kathrine S. H. Beckham, Grzegorz Chojnowski et al. · 0 citations

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