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Author

M. van de Ven

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Open access Jul 2026

A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

Immunity protection from macrophages is revealed as an adverse consequence of hormonal therapy in prostate cancer patients using a genome-wide co-culture CRISPR screen and positions tumor-intrinsic AR signaling as a bona fide immunomodulatory pathway.

Anniek Zaalberg, Audrey Lacoste, Emma Minnee et al. · 0 citations

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