AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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A tiered framework - catalysis, selectivity, producibility, process fit - is proposed for judging whether an AI-designed enzyme is a useful biocatalyst rather than merely a functional protein.
Malonyl-CoA is a major extender unit in polyketide biosynthesis; however, in Escherichia coli, it is predominantly consumed by fatty acid biosynthesis, limiting its availability for heterologous polyketide production. Here, we engineered a fatty acid biosynthesis-β-oxidation carbon-recycling pathway (FABOX pathway) tha...
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