Radiosynthesis and preliminary evaluation of [11C] and [18F] labelled lacosamide scaffolds for brain PET imaging.
This study summarizes the automated, transition-metal-free radiosynthesis approach for producing [11C]LCM and its bioisosteric analogue [18F]FLCM, along with preliminary pharmacological and preclinical evaluations of these radiotracers can act as potent brain imaging radiotracer candidates. Radiosynthesis was carried o...