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Manuel Kleiner

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Open access Sep 2026

Bloom-forming bacteria heavily invest in anti-phage defense

Bacterial blooms are characterized by unusually high cell densities and exceptionally low diversity and can profoundly alter ecosystem function and services. Bacteriophages have long been considered an important cause of mortality in blooms, acting as a mechanism for control. Here, we characterize the viral ecology of...

R. Weed, M. Moynihan, Eleanor Greene et al. · 0 citations
Open access Sep 2026

Conserved inhibitory mechanisms of root-associated bacteria towards Arabidopsis thaliana and Chlamydomonas reinhardtii

Soil bacteria colonize plants without causing visible disease, yet many suppress host growth. The prevalence and evolutionary reach of this cryptic inhibition are unknown, because phenotyping hundreds of isolates in plants is prohibitively slow. Here we use the unicellular algae Chlamydomonas reinhardtii as a scalable...

Tzila Vikinyanski, Elad Meilin, Andrei Makhon et al. · 0 citations
Open access Sep 2026

Anoxygenic phototrophic Chlorobi use broad metabolic and resource acquisition strategies to support stable near-clonal blooms

Anoxygenic phototrophic green sulfur bacteria (GSB; Chlorobiia) are important primary producers in anoxic and sulfidic environments, whose significance in aquatic ecosystems will expand with coastal deoxygenation. Here, we employed a uniquely comprehensive analytical approach to investigate the formation, maintenance,...

M. Moynihan, Olivia L. Mathieson, Catherine A. Crowley et al. · 1 citation
Open access Sep 2026

Stability in flexibility: Shifting alliances stabilize the symbioses of marine animals over 150 million years

Many animals benefit from microbial symbionts that aid digestion, supply essential nutrients, or provide defense. When this dependence becomes obligate, as in gutless marine oligochaetes that have lost both digestive and excretory systems and rely entirely on their bacterial partners for nutrition and recycling of wast...

A. Mankowski, Manuel Kleiner, C. Erséus et al. · 0 citations
Review Open access Jul 2026

TriMic: a Triticum aestivum microbial culture collection and synthetic community for dissecting wheat-microbe interactions

TriMic is established, a taxonomically and functionally representative culture collection of wheat root–associated bacteria that includes high quality genome sequences and an overview of genes involved in plant colonization, nutrient cycling, and plant growth promotion and expanded by designing a reduced complexity Syn...

Clara Tang, A. Zervas, Andrea Ward et al. · 0 citations
Open access Jul 2026

Symbiosis reshapes metabolism of sulfate-reducing bacteria in gutless marine worms.

It is revealed that a globally distributed clade of symbiotic SRB has a conserved core metabolism that diverges from free-living relatives, and these endosymbionts retain key traits of SRB such as sulfate reduction, complete oxidation of acetate to CO2, amino acid degradation for nitrogen acquisition, and transport of...

G. D'Angelo, Manuel Kleiner, A. Mankowski et al. · 0 citations
Open access Aug 2026

Animal degradation of microbial storage polyhydroxyalkanoates.

A wide range of microorganisms produce storage biopolymer polyhydroxyalkanoates (sPHAs) as carbon and energy reserves. However, only bacteria and fungi are known to degrade microbial sPHAs, using enzymes called polyhydroxyalkanoate depolymerases (PHADs). Here we show that some animals also have PHADs that can degrade s...

Caroline Zeidler, H. Gruber-Vodicka, D. Michellod et al. · 0 citations

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