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Marc C. Morais

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#protein folding Review Open access Sep 2026

RNA engineering approaches to aid high-resolution structure determination of medium- to large-sized RNAs.

High-resolution structure determination of RNA remains a major challenge due to its conformational flexibility, intrinsic heterogeneity, and susceptibility to degradation. Although RNA plays central roles in gene regulation, viral replication, and cellular homeostasis, RNA-only structures represent a small fraction of...

Jerricho Tipo, K. Gottipati, Marc C. Morais et al. · 0 citations

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