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Marcello Maresca

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#gene editing Open access Sep 2026

Impact of Genome Editing delivery tools on target cells: Training School Report

The Training School on the Impact of GE Delivery Tools on Target Cells was designed to provide an in-depth overview of delivery strategies for genome editing (GE) tools, a cornerstone for gene therapy and cellular engineering. The ability to efficiently and safely introduce genome editing reagents into diverse target cells remains one of the most critical challenges in advancing translational applications of CRISPR, base editing, and related technologies. This three-day program combined theoretical lectures from international experts with complementary laboratory sessions. The lectures covered delivery vectors and nanoparticles, genome editing platforms, and safety and immunological aspects, while the hands-on sessions focused on evaluating delivery efficiency and editing outcomes using different approaches. Participants had the opportunity to explore both conceptual frameworks and experimental techniques — from lipid nanoparticles and viral vectors to genome editing assessment in primary T cells. The interactive structure of the Training School fostered scientific exchange, critical thinking, and practical skill development.

Carla Fuster‐García, Manuel Rhiel, Duško Lainšček et al. · 0 citations
#gene editing Open access Sep 2026

Impact of Genome Editing delivery tools on target cells: Training School Report

The Training School on the Impact of GE Delivery Tools on Target Cells was designed to provide an in-depth overview of delivery strategies for genome editing (GE) tools, a cornerstone for gene therapy and cellular engineering. The ability to efficiently and safely introduce genome editing reagents into diverse target cells remains one of the most critical challenges in advancing translational applications of CRISPR, base editing, and related technologies. This three-day program combined theoretical lectures from international experts with complementary laboratory sessions. The lectures covered delivery vectors and nanoparticles, genome editing platforms, and safety and immunological aspects, while the hands-on sessions focused on evaluating delivery efficiency and editing outcomes using different approaches. Participants had the opportunity to explore both conceptual frameworks and experimental techniques — from lipid nanoparticles and viral vectors to genome editing assessment in primary T cells. The interactive structure of the Training School fostered scientific exchange, critical thinking, and practical skill development.

Carla Fuster‐García, Manuel Rhiel, Duško Lainšček et al. · 0 citations

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