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Maria S. Rubel

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#protein folding Sep 2026

LNA-Modified DNAzyme Nanomachines Enable Physiological-Temperature Recognition of Double-Stranded DNA

Sequence-specific detection of double-stranded DNA (dsDNA) under physiological conditions remains challenging because the complementary strand is inaccessible to conventional oligonucleotide probes, often requiring thermal denaturation or protein-assisted strand separation. Here, we developed a binary DNAzyme (BiDz)...

M. Ateiah, Vladislav A. Reushev, Nairouz Deeb et al. · 0 citations

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