Uncovering early-stage vaccine candidates against Fasciola hepatica through integrative comparative proteomic analysis and proof-of-concept CRISPR-Cas9 gene editing
Fasciolosis, mainly caused by the liver fluke Fasciola hepatica , is a globally distributed parasitic disease that affects both livestock and humans, generating significant economic losses and public health concerns. Current control strategies rely mainly on anthelmintic treatments, but the increasing emergence of drug...