This review discusses medicinal chemistry approaches primarily targeting HDAC1/2, LSD1, and DNMT1, with emphasis on inhibitor classes, binding mechanisms, structural features, preclinical evidence, and translational limitations, and how a better understanding of γ-globin repression may guide the development of safer an...
Mateus Mello de Souza, A. R. Pavan, Victor Gabriel de Faria Pastre et al.· European journal of medicina...· 0 citations
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