Genome-wide synthetic lethality screen of Bam complex-associated genes in Escherichia coli
Abstract Biogenesis of the bacterial outer membrane is key to bacterial survival and antibiotic resistance. Central to this is the β-barrel assembly machine (Bam) complex and its associated chaperones, which are responsible for transport, folding and insertion of outer membrane proteins (OMPs). The Escherichia coli Bam...
Jack Alfred Bryant, Kara A Staunton, Hannah M. Doherty et al.
· eLife · 1 citation