Matteo Ciciani

Systematic investigation of prokaryotic mobile genetic elements and programmable nucleases using large metagenomic data

In Bacteria and Archaea, mobile genetic elements (MGEs) are extremely diverse in terms of size, structure and mobilization mechanism, ranging from minimal non-autonomous sequences (<100 bp) to complex elements (>100,000 bp) capable of mobilizing many passenger genes. MGEs drive genome evolution and horizontal gene tran...