Open access
Jul 2026
Astrocytes instructively regulate neuronal translation
It is shown that astrocyte-secreted proteins regulate global neuronal translation depending on astrocytic state, and astrocyte-secreted signals required neuronal endocytosis to influence translation and drove synaptic remodeling dependent on glutamatergic signaling and neuronal mTORC1 activity.
Wendy J Liu, Carson C Schultz, Eshaan A Khan et al.
· bioRxiv · 0 citations