Photo-Activatable RNA Switches for Optical Control of Cell-Free Protein Synthesis
Programmable RNA switches enable target-dependent regulation of cell-free protein synthesis. Here, we report a photo-activatable RNA switch using photocleavable Lock DNA (pcl-Lock) to enable optical control of in vitro translation. Synthesized by solid-phase methods, pcl-Lock incorporates a coumarin-based photocleava...
Natalie E. Connell, Mahla Lashkari, Emmett Hanson et al.
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