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Meng-Ying Liu

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#gene editing Review Open access Aug 2026

Applications and Future Perspectives of CRISPR/Cas9 Gene Editing Technologies in CAR-T Cell Therapy

In general, CRISPR/Cas9-based engineering is a promising way of developing the next generation of precision cancer immunotherapy and is likely to be improved further in future through advancements in genome editing technology, delivery methods, and synthetic biology.

Meng-Ying Liu · International Journal of Bio... · 0 citations

Jul 2026

Efficient and precise programmable DNA knock-in without double-strand breaks

Kilobase-scale nickase-targeting (KNIT) editing enables single-nick-based DNA insertion across genomic loci and cell types, supporting insertion of DNA fragments exceeding 10 kb, with high efficiency and minimal unwanted off-target effects.

Yanmin Gao, Yu Ma, Ke-Xin Yu et al. · Nature · 0 citations