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Author

Michael C. Donohue

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Review Open access Sep 2026

Research satisfaction among participants in a preclinical Alzheimer's disease trial

Empirical data capturing participants’ experiences in preclinical Alzheimer's disease (AD) trials are limited. We examined participant responses on a Research Satisfaction Survey (RSS) from the Anti‐Amyloid Treatment in Asymptomatic AD Study.

Marina Ritchie, K. Hussen, O. Langford et al. · 0 citations
Open access Aug 2026

Stages of objective memory impairment (SOMI) as a predictor of clinical progression in the A4 study

SOMI’s risk profile in A4 was similar to prior findings in observational cohorts, and provides a low-cost, non-invasive enrichment tool for identifying individuals at risk for early cognitive decline in secondary prevention trials.

Priyanka Kumari, R. Lipton, A. Aschenbrenner et al. · 0 citations
Open access Sep 2026

CSF proteomics and machine learning reveal distinct stages across the Alzheimer’s disease continuum

These findings uncover protein signatures that reflect underlying AD biology and provide a foundation for stage-specific biomarkers and therapeutic targeting, with important implications for patient stratification and personalized intervention strategies.

Saima Rathore, E. Dammer, Anantharaman Shantaraman et al. · 0 citations

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