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Author

Michael P. Gustafson

2 papers indexed here

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Review Open access Aug 2026

A proposal of good manufacturing practices (GMP) laboratory for CAR T-cell therapy in Latin America and the Caribbean: challenges and opportunities

This model advocates for decentralized, modular cleanroom facilities that integrate fully closed automated manufacturing platforms with risk-based quality management systems and emphasizes the strategic implementation of artificial intelligence (AI) and digital health tools—such as electronic batch records and predicti...

S. Cabrera-Salcedo, L. Parra-Lara, Mónica Fernandes-Pineda et al. · 0 citations
#protein folding Open access Sep 2026

Engineered mRNA nanostructures expand the design space of mRNA therapeutics through programmable protein expression and immune stimulation

Messenger RNA (mRNA) therapeutics have transformed vaccination and protein replacement strategies, yet efforts to improve their performance have focused largely on sequence engineering, nucleotide modification, and delivery vehicles. Here we show that mRNA function can be controlled by rational design of higher-order R...

Mark D. Knappenberger, S. J. Henry, Archana Kikla et al. · 0 citations

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