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Author

Michał Maj

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Review 2026

Cryo-EM of amyloid fibrils: Advances, challenges, and translational applications.

The persistent bottleneck of sample preparation is addressed, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems, and the translational value of high-resolution maps is highlighted, demonstrating how they enable the rational, structure-based d...

Dylan Valli, Michał Maj · 0 citations
#protein folding Open access Aug 2026

Secondary nucleation drives polymorph diversity in hIAPP amyloids

Amyloid fibrils are implicated in a myriad of human diseases. A striking observation is that fibrils extracted from diseased tissues are characterized by a restricted set of folds unique to the specific pathology. In contrast, fibrils grown in vitro exhibit extensive structural diversity, suggesting that specific envir...

Mikołaj I Kuska, Łucja Kozicka, S. Prodhan et al. · 0 citations

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