Author

Minfeng Wang

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Open access Aug 2026

D-mannose blocks S-adenosylmethionine generation to suppress macrophage IL-1β expression

Background and aims Inflammatory stimuli drive metabolic reprogramming in macrophages, supplying energy, reducing equivalents, and methyl donors required for the production of inflammatory mediators such as IL-1β; however, metabolic strategies to regulate this pathway remain unclear. Here, we aimed to define the mechan...

Yingyi Chen, Junji Xu, Jing-Fei Fu et al. · Frontiers in Immunology · 0 citations

#protein folding Open access Aug 2026

Dehydrocorydaline Accelerates Palatal Wound Healing in Mice Through Suppression of the p38 MAPK/CCL2 Axis and Macrophage Chemotaxis: A Preliminary Study

Investigating whether DHC accelerates palatal wound healing and to elucidate the role of the p38 mitogen-activated protein kinase (MAPK)/CCL2 signaling axis in DHC-mediated regulation of macrophage chemotaxis demonstrated that DHC accelerated palatal wound healing 1.6-fold in mice.

Yingyi Chen, Zhao-Nan Liu, Yi-Jia Wang et al. · Biomedicines · 0 citations