Author

Mohamed M. Tawfik

2 papers indexed here

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#protein folding Open access Nov 2026

Hylocereus undatus peel extract and ZnO nanoparticles suppress cancer through apoptosis and Wnt/β-catenin inhibition

Among all tested formulations, ZnO NPs-AE showed the strongest antitumor activity, both in cell culture (Caco‑2 and HepG2) and in the Ehrlich ascites carcinoma mouse model, and represents a promising, well tolerated biogenic nanoplatform for targeted cancer therapy.

Mohamed M. Tawfik, Lamiaa A. A. Barakat, Hoda W. Elfeky et al. · Scientific Reports · 0 citations

Open access Jul 2026

Design, synthesis, molecular docking and molecular dynamics simulations of pyrazolo[3,4-d]pyrimidine scaffolds as selective COX-2 and CDK2 kinase inhibitors with dual anti-inflammatory and anti-proliferative activities

A new series of pyrazolo[3,4-d-d]pyrimidine scaffolds, namely, 4a–l, were designed, synthesized, and tested for anti-inflammatory and anti-proliferative activities and represent promising starting candidates for the development of future CDK2 kinase and COX-2 inhibitors.

Sara Y. Ewieda, Laila Ziko, Ahmed Elshewy et al. · RSC Advances · 1 citation