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Author

Mohaned Adil

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Review Open access Aug 2026

Tumor‐Associated Macrophages in the Chemoresistant Microenvironment of Gastric Cancer: Key Mechanisms and Intercellular Crosstalk

Current evidence on TAM‐driven chemoresistance in GC is synthesized, highlighting the molecular interplay between TAMs, tumor cells, and stromal components and underscores the potential of TAM‐centric therapies to overcome resistance and improve clinical outcomes.

S. Abdul-Rahman, Abdulkareem Shareef, S. Jyothi et al. · 0 citations
Review 2026

AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery

The strategies detailed here define a next-generation precision-oncology paradigm capable of anticipating tumor evolution, overcoming resistance, and preventing metastatic relapse, by uniting AI-guided design, circadian reprogramming, dormancy eradication, and logic-gated delivery.

Anmar Ghanim Taki, Abdulkareem Shareef, Vimal Arora et al. · 0 citations
Review Jul 2026

Peptide Loading Complex in Cancer: From Peptide Translocation, Editing, and Loading into MHC-I to a Potential Therapeutic Target

An overview of the PLC as a major determinant of tumor immune escape and a potential therapy target is provided and existing or evolving therapeutic approaches to recover/reprogram PLC functions are explored.

O. Allela, Abdulkareem Shareef, Hayder Naji Sameer et al. · 0 citations

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