Coordinated mitochondrial quality control underlies oxidative stress resilience in MUSE stem cells
Reactive oxygen species (ROS) regulate stem-cell function, but sustained exposure causes oxidative damage, mitochondrial dysfunction and exhaustion. Multilineage-differentiating Stress-Enduring (MUSE) cells, a rare SSEA-3⁺ MSC subset, tolerate ROS-rich environments, although the mechanisms remain unclear. We compared M...
Domenico Aprile, Sura Hilal Ahmed Al-Sammarraie, Alessia Ambrosino et al.
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