Muhammet Sait Eyerci

Calcium-associated Pro367 ring puckering supports conformational selection in a thermophilic lipase

Thermophilic bacterial lipases must combine structural stability with the conformational flexibility required for interfacial activation, yet the local organization of their metal-binding sites remains incompletely understood. Here, we determined two X-ray crystal structures of the family I.5 lipase from Geobacillus ka...