Muralidharan Jothimani

In silico analysis of SH3BP2 genomic alterations and expression profiles in CRC.

AIM Colorectal cancer (CRC) is a widespread health issue that attains high mortality. The adaptor protein SH3BP2 amplification results in metabolic changes, oxidative stress, NK cell activity, and inflammation. The NK cells are capable of destroying tumor cells without prior activation, help prevent metastasis, and hav...