Hedgehog-related gene wrt-10 mediates intergenerational effects of fasting on larval size in Caenorhabditis elegans
It is found that reproductively aged wild-type worms and wrt-10 ( aus36 ) null mutants both had a greater likelihood of progeny production after 24-h or 48-h fasting periods in early adulthood, indicating that wrt-10 is not required for this response, and wrt-10 may enable diet-restricted C. elegans adults to channel r...