Mustafa Cengiz

Ceranib-2 potentiates cisplatin activity under an experimental in vitro hipec-like model by inducing integrated stress and cell death pathways in ovarian cancer

This study aims to investigate whether the addition of Ceranib-2, an acid ceramidase inhibitor, could enhance the cytotoxic efficacy of cisplatin under hyperthermic conditions using an OVCAR-3 ovarian cancer cell model. The combination of cisplatin and ceranib-2, administered at a tolerable hyperthermic temperature o...

Carmofur inhibits ovarian cancer cell proliferation, migration, and invasion via disrupting the YAP-1/TEAD pathway: in vitro and in silico approaches