Autotaxin induces fibrosis in lamina cribrosa cells in glaucoma
Lysophosphatidic acid (LPA) and the enzyme that generates it, autotaxin, have been shown to play a role in fibrosis in the trabecular meshwork in glaucoma, contributing to increased intraocular pressure. We wished to investigate the role of LPA and autotaxin in fibrosis of the lamina cribrosa (LC) of the optic nerve he...
Amy O’Regan, Mustapha Irnaten, Sarah Eivers et al.
· Scientific Reports · 0 citations