Author

Nonlawat Boonyalai

2 papers indexed here

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#protein folding Oct 2026

Potent reaction hijacking inhibitors of Plasmodium falciparum asparagine tRNA synthetase

ABSTRACT Malaria remains one of the major threats to human health. Breakthrough drugs with high potency and low resistance risk are needed to combat the ever-increasing resistance to currently deployed antimalarials. Here, we explore a series of 4-aminoquinazoline-based sulfonamides (4AQS), with a synthetically accessi...

Xi Ye, Lisl Y. Esherick, Nutpakal Ketprasit et al. · mBio · 0 citations

Open access Aug 2026

Discovery of Sphaeriaurantins as Rapid-Acting Antiplasmodials with Dual Activity in Blood and Liver Stages

The rapid emergence of resistance in the malaria-causing protozoan Plasmodium falciparum has heightened the demand for treatments with novel modes of action. Having evolved to produce a myriad of structurally diverse natural products (NPs) as defenses against soil-dwelling parasites including protozoa, Actinomycetota s...

Chantal D. Bader, Jennifer E. Collins, Yue-Lan Li et al. · Journal of the American Chem... · 0 citations