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Meta-analysis Open access Sep 2026

Effectiveness, safety and acceptability of continuous or extended-cycle use of combined oral contraceptives (COCs): a systematic review and meta-analysis.

BACKGROUND To evaluate the contraceptive effectiveness, safety and acceptability of continuous or extended-cycle combined oral contraceptives (COCs) compared with conventional cyclic regimens (21/7 or 24/4). METHODS A systematic search was conducted in Medline, Embase, Web of Science, trials registries and other data...

Li Jiang, Maya Kshatriya, Z. Bhutta et al. · 0 citations
Review Open access Sep 2026

Contraceptive effectiveness and safety of ormeloxifene: a systematic review.

Ormeloxifene shows promise as a moderately effective, safe and user-acceptable contraceptive option among reproductive-age women and support its inclusion in global contraceptive guidelines.

TH Tufa, Muhammad Idrees, G. Odey et al. · 1 citation
Review Open access Sep 2026

Efficacy, safety and acceptability of the use of 68 mg etonogestrel contraceptive subdermal implant for up to 5 years compared with up to 3 years: a systematic review.

Current evidence, despite its low certainty, does not carry signals of potential concerns with regard to extended use of the etonogestrel implant, with potential for benefit.

Jessica Chen, J. Sothornwit, Asantesana Kamuyango et al. · 1 citation

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