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N. Orlova

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#protein folding Open access Aug 2026

DTT-Induced Transcriptome Profiling Reveals Divergent ER Proteostasis and Stress-Adaptation Programs in CHO-S/HB8 and CHO-4BGD/DUL Producer Clones

The producers occupy distinct ER-proteostasis states, and DUL mounts a broader, but not uniformly stronger, canonical UPR response to reductive ER stress.

N. Orlova, N. A. Potapova, R. R. Shaifutdinov et al. · 0 citations