Male breast cancer (MBC) is rare and remains largely managed using knowledge derived from female breast cancer. Here, we generated a multiplatform single-cell and spatial transcriptomic atlas integrating scRNA-seq, SeekSpace, Visium HD, Xenium In Situ, and multiplex immunohistochemistry data from male and female breast...
Hao-Yuan Shi, Xiu-Li Zhang, Shou-Liang Cai et al.· Science Advances· 0 citations
INTRODUCTION
Hypothesis-driven studies have identified many modifiable cancer risk factors, but research focusing on single exposures overlooks their complex interactions.
OBJECTIVES
This study applied an exposome-wide approach across multiple cancer types to systematically identify modifiable exposures and evaluate...
Wen Liu, Shuai Xiang, Yi-Wei Liu et al.· Journal of Advanced Research· 0 citations
A reciprocal circuit in which cuproptotic tumor cells promote dendritic cell activation and CD8+ T cell priming, whereas T cell-derived IFN-γ sensitizes tumor cells to FDX1-dependent cuproptosis is revealed.
Yun Gao, N. Xing· Cell· 1 citation
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