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Negar Sadeghi

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#gene editing Review Open access Sep 2026

Rewriting the cancer epigenome: CRISPR technologies for DNA methylation editing

This review synthesizes current advances in CRISPR-based DNA methylation editing for cancer epigenomics, critically evaluates key challenges, including off-target activity, context-dependent outcomes, delivery and durability, and outlines future directions integrating locus-specific editing with multi-omics profiling,...

Negar Sadeghi, E. Rodger, Aniruddha Chatterjee · 0 citations

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