Sep 2026
An alignment-last approach enables rapid transcriptomic biomarker discovery in large cohorts
Unsupervised read-level differential analysis recovers established lncRNA biomarkers; uncovers new prognostic transposable-element reads in adrenocortical carcinoma and sarcomas; and extracts signals even from reads that fail to align.
Erkan Narmanli, Alexandre Lanau, Mara Neacsu et al.
· bioRxiv · 0 citations