Oscar Mingtian Li

Individualized and Platform-Designated Gene-Editing Studies in the Registered Clinical Record: A Case-by-Case Census Against 148 Eligible Studies

IntroductionIn February 2025, a single infant with carbamoyl phosphate synthetase 1 deficiency received a customized base-editing therapy, and individualized gene editing has since been discussed as an emerging category of care.No one has yet counted whether this category exists in the registered study record. MethodsW...

Digital Twins and Offline Reinforcement Learning for Mechanical Circulatory Support Decisions: What the Current Evidence Can and Cannot Support