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Author

P. Blombery

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Open access Sep 2026

Lenalidomide maintenance after initial immunochemotherapy in chronic lymphocytic leukaemia-Final analysis of the international phase III CLL6 RESIDUUM study of the ALLG and FILO groups.

Most patients treated for chronic lymphocytic leukaemia (CLL) fail to achieve measurable residual disease (MRD) negativity. The role of maintenance with the immunomodulatory drug lenalidomide in these patients is unclear. A randomised multicentre phase III trial (ACTRN12610000060044) was conducted in Australia and Fran...

T. Aurran-Schleinitz, R. Letestu, M. Sartor et al. · 0 citations
Review Jul 2026

CRISPR in clinical oncology: translational advances from molecular diagnostics to therapeutics.

How CRISPR-enabled functional genomics approaches can reveal unexpected cancer dependencies and resistance mechanisms is outlined, and emerging applications of CRISPR-based diagnostics in oncology that convert precise nucleic acid sequence recognition into rapid mutation detection are discussed.

S. Grigg, Carolyn Shembrey, M. Fareh et al. · 1 citation

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