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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Patricia L. Clark

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Open access Aug 2026

Efficient experimental characterization of the GPCRome via deep receptor scanning

G protein-coupled receptors (GPCRs) mediate a variety of signaling pathways and represent the most common class of pharmaceutical target. While advances in structural biochemistry have provided deep functional insights into key receptors, many of the 800+ human GPCRs remain understudied. We introduce a versatile “deep...

A. Tedman, Muskan Goel, Sohan S. Shah et al. · 0 citations
#protein folding Open access Aug 2026

Autotransporter folding avoids a kinetic trap during vectorial translocation across the bacterial outer membrane

This work introduces BEAM, a multiscale framework that learns slow collective variables from coarse-grained simulations to guide all-atom enhanced sampling to explain how vectorial secretion accelerates pertactin folding by excluding an off-pathway kinetic trap.

Lan Yang, Qing Luan, Michael C. Baxa et al. · 0 citations

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