Clinical, genetic, and neuropathologic correlates of limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC): A systematic review and meta-analysis.
A first-of-its-kind meta-analysis outlines a distinct pattern of correlates associated with LATE-NC, emphasizing its strong linkage to AD-related and multimorbid neuropathologic processes, and underscoring the need for refined diagnostic frameworks and future mechanistic studies to differentiate LATE-NC from coexisting...