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Author

Phool Chandra

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Review Oct 2026

Prolactin and Neuroendocrine Regulation in Brain Injury: Mechanisms of Adaptive Plasticity and Therapy Strategies.

BACKGROUND Acquired Brain Injuries (ABIs) represent a significant worldwide health challenge, with few specific medicines available to enhance recovery. Growing data underscores neuroendocrine dysfunction, especially with prolactin as a relatively overlooked yet potentially alterable element in neuronal regeneration. H...

Prashant Tiwari, Phool Chandra, Sunil Kumar Kadiri · 0 citations
Open access Aug 2026

Design and Validation of a Reverse Phase HPLC Method for Simultaneous Determination of Doxycycline and Metronidazole in Targeted Periodontal Therapy

The reverse-phase high-performance liquid chromatography (RP-HPLC) method has been shown to exhibit excellent repeatability, accuracy, and reproducibility when used to simultaneously assess doxycycline and metronidazole for the management of localised periodontal diseases.Low levels of interference were achieved throug...

Anuj Kumar, Phool Chandra, Anurag Verma et al. · 0 citations
Review Open access Sep 2026

Microbiome-gut-brain axis modulation for the management of Parkinson's disease: Emerging mechanisms and translational insights.

Parkinson's disease (PD) is a progressive neurodegenerative disease that is associated with the loss of dopaminergic neurons and the formation of α-synuclein aggregates in the brain. Changes in the gut microbiota have been closely associated with PD pathophysiology and may contribute to disease-related processes throug...

Madhavi Porwal, R. Malviya, Phool Chandra et al. · 0 citations
Aug 2026

Flavonoid-Enriched Extract of Carissa carandas Linn Triggers Apoptosis and Cell Cycle Arrest in A549 Lung Cancer Cells: An Integrated In-Vitro and In-silico Approach Targeting CDK2 and Bcl-2

The findings suggest that EECC exerts anticancer effects against A549 lung carcinoma cells primarily through ROS-mediated apoptosis and cell cycle arrest.

Priyanka Bajpai, Phool Chandra, Om Prakash · 0 citations
Aug 2026

Microbial Metabolites as Systemic Signaling Molecules: Integrating Metabolism, Immunity, and Organ Crosstalk in Health and Disease.

The integration of multi-omics technologies, artificial intelligence, and precision microbiome-based interventions is expected to accelerate the development of personalized therapeutic strategies and enhance the clinical applicability of microbial metabolite research.

Amit Kumar, Phool Chandra, Prakhar Varshney et al. · 0 citations
Open access Jul 2026

In-silico molecular design approach of some phytoconstituents from Nardostachys jatamansi as HIV/AIDS agents

The therapeutic relevance of N. jatamansi-derived compounds through in-silico evaluation as antiviral agents targeting HIV-1 reverse transcriptase is supported and warrant further in-vitro and in-vivo studies to explore their role as novel antiretroviral agents.

Mohammad Asif, Mazen M. Almehmadi, A. Alzahrani et al. · 0 citations
Review Aug 2026

Physicochemical Science of Electrospun Nanofibers as Drug Delivery Systems for Improved Clinical Outcomes

The interactive combination of physics‐based structural engineering and chemistry‐based functional modification offers an efficient framework for developing the next‐generation nanofiber‐based drug delivery systems.

Madhavi Porwal, Phool Chandra, S. Sridhar et al. · 0 citations

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