The therapeutic relevance of N. jatamansi-derived compounds through in-silico evaluation as antiviral agents targeting HIV-1 reverse transcriptase is supported and warrant further in-vitro and in-vivo studies to explore their role as novel antiretroviral agents.
Findings suggest that bioactive compounds from E. officinalis may serve as promising candidates for the development of anti-CHIKV therapeutics, however, further experimental validation is required to confirm their efficacy and safety.
R. Daman, M. Miglani· Genetics and Molecular Resea...· 0 citations
Findings suggest P. macrocarpa phytochemicals may serve as natural alternatives to existing antiviral treatments, warranting further experimental validation.
Fatin Hannani Mohd Shaharizal, N. Alias, Sin-Ang Lee et al.· Malaysian Journal of Science...· 0 citations
It is highlighted that phytocompounds from Hydrocotyle javanica exhibit significant binding affinity toward key enterobacterial targets, along with favorable ADME and toxicity profiles, which suggest their potential as promising lead molecules for anti-enterobacterial drug development, warranting further experimental v...
Debasmita Paul, M. Ghosh, Manab Mandal· Bioresources and Bioprocessi...· 0 citations
This study conducted an in silico evaluation of dehydrocostus lactone (DHCL) from Echinops kebericho to validate its ethnopharmacological use as an antimicrobial agent, performed at 02:20 PM EAT on Monday, August 04, 2025. Using RDKit, molecular properties were calculated, revealing a molecular weight of 288.34 g/mol,...
Belay Sitotaw. Goshu, M. M. Woldeamanueal· Brazilian Journal of Science· 0 citations
Salvia miltiorrhiza Bunge (Lamiaceae) is a traditional medicinal plant rich in bioactive tanshinones with diverse pharmacological properties. However, comparative information regarding experimentally measured activity and computational interaction profiles of individual tanshinones remains limited. This study aimed to...
M. C. Nguyen, Minh-Tri Le, Huynh Nguyen Khanh Tran· RSC Advances· 0 citations
Findings indicate that the tested compounds possess potential as antibacterial and quorum sensing inhibitory agents by targeting LuxR, however, further in vitro and in vivostudies are required to validate their biological activity and therapeutic potential.
Ziyan Iswahyudi, M. Fadjar, Y. Maimunah et al.· Journal of aquaculture and f...· 0 citations
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