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#protein folding Open access Sep 2026

Specific host translation perturbations promote TnSmu1 loss independently of the canonical ImmA regulator

These findings identify host translational state as an important physiological determinant of TnSmu1 stability and reveal that bacterial hosts can influence the maintenance of integrated mobile genetic elements through mechanisms that extend beyond element-encoded regulatory circuits.

Liang Bao, T. Kitten, Ping Xu · 0 citations
Open access Aug 2026

A genome-wide in vivo screen reveals fitness pathways required for streptococcal infective endocarditis

Infective endocarditis (IE) is a life-threatening disease most often caused by blood-borne bacteria that infect previously damaged cardiac tissue. Despite the importance of this disease, the genetic basis for IE-associated fitness remains poorly defined. Here, we present the first genome-wide in vivo analysis of bacter...

Liang Bao, Jennifer Bradley, Vysakh Anandan et al. · 0 citations

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