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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Pingping Wang

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#protein folding Oct 2026

A transferable perturbation proteomics framework for phenotype- 1 based annotation and antiproliferative potency scoring of antineoplastic agents

Although antineoplastic agents target diverse proteins, whether they converge on conserved cellular response states remains unclear. Here, we generate a TMTpro 18-plex quantitative proteomics atlas of 367 antineoplastic agents in HepG2 cells and identify recurrent drug response phenotypes (DRPs). The higher-order organ...

Jing Liang, Jundan Tian, Rui Zhang et al. · 0 citations

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