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Author

Prabir Roy-Chaudhury

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2 papers indexed here

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Open access Sep 2026

Alterations of Gene Expression and Signaling Pathway Activity in Venous Smooth Muscle Cells After Uremic Serum Exposure

Uremia is the most common pathophysiological symptom in chronic kidney disease (CKD) patients, particularly in end-stage kidney disease (ESKD) patients. Uremia can lead to several vein-specific vascular diseases, such as renal vein thrombosis (RVT), deep vein thrombosis (DVT) and dialysis access-induced venous stenosis...

You-You Zheng, U. Uriyanghai, C. Wai et al. · 0 citations
#protein folding Open access Aug 2026

Uremic Serum Alters Gene Expression Profiles and Signaling Pathway Activity in Porcine Arterial Smooth Muscle Cells

The signaling pathways that regulate cellular redox homeostasis, the cellular waste disposal system, ER stress and autophagy are major signaling pathways involved in aSMCs’ responses to uremic serum exposure, which may contribute to the severe arterial-specific clinical symptoms observed in CKD/ESKD patients.

You-You Zheng, Kent A. Lee, U. Uriyanghai et al. · 0 citations

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