Author

Prashant Kumar

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#gene editing Review Open access Nov 2026

Smart nanomaterials for the delivery of gene editors: beyond LNPs

The era of genetic medicine is rapidly unfolding, with major advances in tools for gene editing, silencing, and replacement. Gene editing machinery is versatile and can be delivered in the form of DNA (e.g., plasmids), RNA (e.g., mRNA and guide RNA) or directly in protein form as a ribonucleoprotein complex (RNP). Ye...

Ina Guri-Lamce, Isabelle Benson, Prashant Kumar et al. · Frontiers in Nanotechnology · 0 citations

Open access Oct 2026

Mechanisms of CD4+ T tolerance to a corneal epithelial neoantigen.

Tissue-specific peripheral tolerance mechanisms are essential to prevent autoimmunity. The cornea is immune privileged, and anterior chamber-associated immune deviation (ACAID) governs its inner surface. However, the mechanisms governing corneal epithelial (outer surface) antigens remain unknown. Using an inducible, co...

J. Galletti, Kaitlin K. Scholand, Jian-Ming Shao et al. · Mucosal Immunology · 0 citations