TPGS-stabilized pyrimethamine micelles promote ROS-associated apoptosis in MDA-MB-231 cells and suppress tumour progression in a murine lymphoma model
TPGS–pyrimethamine micelles enhance cellular uptake and are associated with increased ROS generation, apoptosis, and cell-cycle alterations in MDA-MB-231 cells, together with tumour suppression in a murine lymphoma model, which support further preclinical investigation of TPGS-based pyrimethamine micelles as a potentia...