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Review Open access Aug 2026

Potential mechanisms by which microbiota-accessible carbohydrates regulate hepatic lipid metabolism in MAFLD via the gut-liver axis

Metabolic dysfunction-associated fatty liver disease (MAFLD) is a prevalent chronic metabolic liver disorder, whose onset and progression are closely associated with dysregulated lipid metabolism, chronic inflammation, and intestinal microbial dysbiosis. The gut and liver are anatomically and functionally connected via...

Jing-Yi Peng, Xiao-Jiao Gao, Guang-Lei Chen et al. · 0 citations
#gene editing Review Open access Sep 2026

The role of lysine acylation in metabolic dysregulation and inflammatory responses within the hepatic immune microenvironment of MASLD

Metabolic dysfunction–associated steatotic liver disease (MASLD) is a chronic liver disorder characterized by metabolic abnormalities, persistent low-grade inflammation, and alterations in hepatic immune function. In addition to lipid accumulation and dysregulated energy metabolism, metabolism-associated post-translati...

Jing-Yi Peng, Ankangxin Yan, Guang-Lei Chen et al. · 0 citations

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