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Qianqian Ni

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Oct 2026

Terminal-overhang-restricted CRISPR logic nanodevice for precision cancer therapy.

The limited precision of controlled drug release remains a major challenge for precision cancer therapy. Herein, a protein and nucleic acid dual-biomarker-responsive CRISPR AND logic nanodevice, termed LogiCas, is developed by integrating APE1 and miRNA-21 as dual inputs for precise tumor therapy. Leveraging the string...

Jing-Ge Zhang, Yu-He Yang, Yong-Hua Wu et al. · 0 citations
Review Open access Jul 2026

Precision chemical engineering of dendrimers for nucleic acid delivery

Future progress of dendrimers will be accelerated by more simplified and easily scalable synthetic processes, enhanced targeting to specific tissues and cells, as well as artificial intelligence-assisted design and optimization to posture dendrimers as a next-generation platform for nucleic acid delivery and precision...

Qianqian Ni, D. Tomalia, Jing Wu et al. · 1 citation

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